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KMID : 0903519900330020169
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1990 Volume.33 No. 2 p.169 ~ p.173
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Inhibitory effects of grapefruit seed extract(DF - 100) on growth and toxin production of Penicillium islandicum
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Abstract
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The anthraquionone mycotoxin, skyrin, is produced by Penicillium islandicum. DF-100 which was extracted from grapfruit seed extract and is a natural organic complex inhibited the biosynthesis of skyrin by Penicillium islandicum. This study way carried out to determine the potential of DF-100 to support Penicillium islandicum and skyrin production. DF-100 inhibited the growth of the fungus at 750ppm or less and caused complete inhibition of skyrin production at 500ppm or less. DF-100 appears to block the incorporation of emodinathrone into skyrin and an enzymatic step in the skyrin biosynthetic pathway which lies before skyrinanthrone.
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